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DNA methylome profiling of maternal peripheral blood and placentas reveal potential fetal DNA markers for non-invasive prenatal testing

4 Jul 2014

Abstract excerpt

Utilizing epigenetic (DNA methylation) differences to differentiate between maternal peripheral blood (PBL) and fetal (placental) DNA has been a promising strategy for non-invasive prenatal testing (NIPT). However, the differentially methylated regions (DMRs) have yet to be fully ascertained. In the present study, we performed genome-wide comparative methylome analysis between maternal PBL and placental DNA from...

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Share to Epigenetics and DNA Methylation
Share to Fetal and Pediatric Neurological Disorders
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PMID: 24996894
DOI: 10.1093/molehr/gau048

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