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Article

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions.

Bioinformatics (Oxford, England) - 12 Dec 2004

Hupé Philippe, Stransky Nicolas, Thiery Jean-Paul, Radvanyi François, Barillot Emmanuel

Abstract excerpt

MOTIVATION: Genomic DNA regions are frequently lost or gained during tumor progression. Array Comparative Genomic Hybridization (array CGH) technology makes it possible to assess these changes in DNA in cancers, by comparison with a normal reference. The identification of systematically deleted or amplified genomic regions in a set of tumors enables biologists to identify genes involved in cancer progression...

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PMID: 15381628
DOI: 10.1093/bioinformatics/bth418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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