Article

TMEM65-dependent Ca <sup>2+</sup> extrusion safeguards mitochondrial homeostasis

2023-10-11

Abstract excerpt

The bidirectional transport of Ca 2+ into and out of mitochondria is a conserved biological process controlling multiple events, including metabolism, signaling, and cell fate. In the presence of membrane potential driving mitochondrial Ca 2+ accumulation, transient changes of [Ca 2+ ] mt in response to cytosolic [Ca 2+ ] variations are ensured by a molecular machinery for Ca 2+ influx and efflux embedded in...

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Literature Corpus work: 0a259a0e-faae-51e1-a481-3977be3f1e41
DOI: 10.1101/2023.10.10.561661

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