Article

A comprehensive genetic characterisation of the mitochondrial Ca <sup>2+</sup> uniporter in <i>Drosophila</i>

2018-10-31

Abstract excerpt

Mitochondrial Ca 2+ uptake is an important mediator of metabolism and cell death. Identification of components of the highly conserved mitochondrial Ca 2+ uniporter has opened it up to genetic analysis in model organisms. Here we report a comprehensive genetic characterisation of the known uniporter components conserved in Drosophila . While loss of MCU or EMRE abolishes fast mitochondrial Ca 2+ uptake, this...

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Literature Corpus work: f356b2f1-c635-5c88-b1b2-af08d3c897b5
DOI: 10.1101/458174

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