Article

Nrf2 regulates ICAM-1–mediated neutrophil extracellular trap formation after traumatic brain injury

2026-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Traumatic brain injury (TBI) triggers secondary neurovascular damage characterized by oxidative stress, blood-brain barrier (BBB) disruption, and neuroinflammation, leading to long-term cognitive deficits. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of cellular antioxidant defense, but its role in maintaining neurovascular integrity after TBI remains unclear. Here, u...

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Literature Corpus work: 0a1c20de-c04a-5dbf-945c-0cdc6e1485b0
DOI: 10.64898/2026.05.01.722360

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