Article

Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury

2023-04-21

Abstract excerpt

<title>Abstract</title><p><bold>Background</bold>Neuroinflammation is one of the most important pathogeneses in secondary brain injury after traumatic brain injury (TBI). Neutrophil extracellular traps (NETs) forming neutrophils were found throughout the brain tissue of TBI patients and elevated plasma NET biomarkers correlated with worse outcomes. However, the biological function and underlying mechanisms of NETs...

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Literature Corpus work: ba36a940-28f9-5b85-84a1-e44d21b78bbf
DOI: 10.21203/rs.3.rs-2834561/v1

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