Article
Influence of Nrf2 genotype on pulmonary NF-kappaB activity and inflammatory response after traumatic brain injury.
Annals of clinical and laboratory science - 1 Jan 2008
Jin Wei, Zhu Lin, Guan Qun, Chen Gang, Wang Qing Feng, Yin Hong Xia, Hang Chun Hua, Shi Ji Xin, Wang Han Dong
Abstract excerpt
Inflammatory response plays an important role in the pathogenesis of acute lung injury (ALI) after traumatic brain injury (TBI). Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that plays a crucial role in cytoprotection against inflammation. The present study explored the influence of Nrf2 genotype on the production of cytokines and on activation of transcription factors in a...
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