Article

Inhibiting YAP1 reduced abdominal aortic aneurysm formation by suppressing adventitial fibroblast phenotype transformation and migration

2024-01-03

Abstract excerpt

<h4>BACKGROUND</h4> The adventitial fibroblast (AF) is the most abundant cell in the vascular adventitia, a few studies had confirmed that AF contributed to abdominal aortic aneurysm (AAA) development; YAP1 involved in several vascular diseases by promoting AF transformed to myofibroblast, the role of YAP1 in AAA is not clear yet. This study aims to determine whether YAP1 play a role in AAA process by regulating...

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Literature Corpus work: 09bfc563-e587-5d15-8d2c-2c6afae7ef7b
DOI: 10.1101/2024.01.02.573973

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