Article

Inhibition of Elastase induced Abdominal Aortic Aneurysm Progression through the CXCL12/CXCR4 Axis via MiR206 3p Sponge

2024-03-22

Abstract excerpt

<h4>Background: </h4> Prior research has established a significant association between the progression of abdominal aortic aneurysms (AAA) and the apoptosis and phenotypic transformation of vascular smooth muscle cells (VSMCs). Notably, the CXCL12/CXCR4 signaling pathway's activation is markedly increased in a mouse model of AAA. Nonetheless, the precise contribution of this pathway to AAA development remains to b...

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Literature Corpus work: f7c46304-b9f8-5fbf-bfc1-fb79b420b959
DOI: 10.21203/rs.3.rs-4119276/v1

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