Article

YAP/TAZ Signaling in Endothelial Cells Mediates the Pathogenesis of Abdominal Aortic Aneurysm Formation

2026-07-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Abdominal aortic aneurysms (AAA) are characterized by dilation of the aorta that can lead to aortic rupture and death. The transcriptional co-activators Yes-Associated Protein (YAP) and WW-domain-containing transcriptional co-activator with PDZ-binding motif (TAZ) are mechanosensitive effectors of the highly conserved Hippo signaling pathway. It is hypothesized that cell-spe...

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Literature Corpus work: c1e5eee2-b868-5c2b-8629-c0c8b34d20a6
DOI: 10.64898/2026.07.01.735919

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