Back to search

Article

Functional Connectivity Alterations in Asymptomatic Familial Early-Onset Alzheimer’s Disease Caused by APP Duplication

2024-09-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND AND OBJECTIVES</h4> Autosomal dominant mutations of Alzheimer’s Disease (AD) are highly penetrant allowing to characterize the asymptomatic phase of this devastating condition. We investigated brain-wide functional alterations in the asymptomatic phase of autosomal dominant early-onset AD (ADEOAD) and explored whether a functional brain fingerprint of the disease can be found prior...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
09ae2b5b-578d-5d2c-b00a-ef3a69b9afa3
DOI
10.1101/2024.09.25.24314362
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Functional Connectivity Alterations in Asymptomatic Familial Early-Onset Alzheimer’s Disease Caused by APP DuplicationDOI 10.1101/2024.09.25.24314362
Select a neighboring publication to make it the new centre.