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Heterogeneous ageing of brain networks across the Alzheimer’s disease continuum

2025-05-14

Abstract excerpt

Accelerated brain ageing has been implicated in Alzheimer’s disease (AD), which is shaped by genetic risk, molecular pathology, and disease processes. However, the spatial heterogeneity of brain ageing patterns across different functional networks along the AD continuum remained largely unexplored. In the present study, we developed a network-specific brain age prediction model trained on structural MRI from 28,34...

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Literature Corpus work
0a79b826-6356-5a6c-9661-78bdbd148cb6
DOI
10.1101/2025.05.14.25327582
Open publication

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Heterogeneous ageing of brain networks across the Alzheimer’s disease continuumDOI 10.1101/2025.05.14.25327582
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