Article

Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy

2026-08-20

Abstract excerpt

Epigenetic clocks based on DNA methylation patterns are among the most accurate molecular correlates of chronological age, yet widely used clocks are predominantly empirical models with limited explicit characterization of the underlying methylation variability, lacking a direct connection to the physical mechanisms of aging. In this work, we bridge this gap by introducing an information-theoretic framework for DN...

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Literature Corpus work: 0983bc67-5c39-5271-ad9e-8a73a90d2138
DOI: 10.64898/2026.08.15.745036

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