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In-depth characterization of the DNA methylation aging landscape links epigenetic noise and genotype-specific epigenetic aging to inflammaging

2026-08-29

Abstract excerpt

<title>Abstract</title> <p>According to recent estimates, over 50% of the human DNA methylome (DNAm) changes with age. These age-associated changes display a significant diversity of patterns that have not yet undergone any comprehensive characterization. Based on a priori-knowledge we here guide a deep-learning based convolutional neural network to classify over 800,000 CpGs in blood into 10 distinct age-related...

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Literature Corpus work: a42223ab-33d6-58d3-a164-5763523f5c81
DOI: 10.21203/rs.3.rs-10584417/v1

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