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AltumAge: A Pan-Tissue DNA-Methylation Epigenetic Clock Based on Deep Learning

2021-06-01

Abstract excerpt

Several age predictors based on DNA methylation, dubbed epigenetic clocks, have been created in recent years, with the vast majority based on regularized linear regression. This study explores the improvement in the performance and interpretation of epigenetic clocks using deep learning. First, we gathered 143 publicly available data sets from several human tissues to develop AltumAge, a neural network framework t...

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Identifiers and source

Literature Corpus work
08da5613-1a54-5896-a8d5-0fbd87269f7f
DOI
10.1101/2021.06.01.446559
Open publication

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AltumAge: A Pan-Tissue DNA-Methylation Epigenetic Clock Based on Deep LearningDOI 10.1101/2021.06.01.446559
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