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Recent Updates on the Significance of KRAS Mutations in Colorectal Cancer Biology.

Cells - 17 Mar 2021

László Loretta, Kurilla Anita, Takács Tamás, Kudlik Gyöngyi, Koprivanacz Kitti, Buday László, Vas Virag

Abstract excerpt

The most commonly mutated isoform of RAS among all cancer subtypes is KRAS. In this review, we focus on the special role of KRAS mutations in colorectal cancer (CRC), aiming to collect recent data on KRAS-driven enhanced cell signalling, in vitro and in vivo research models, and CRC development-related processes such as metastasis and cancer stem cell formation. We attempt to cover the diverse nature of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 33802849
DOI: 10.3390/cells10030667
PMCID: PMC8002639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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