Article
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction.
Psychiatric genetics - 1 Oct 2010
Nielsen David A, Ji Fei, Yuferov Vadim, Ho Ann, He Chunsheng, Ott Jurg, Kreek Mary Jeanne
Abstract excerpt
OBJECTIVES: We have used genome-wide association studies to identify variants that are associated with vulnerability to develop heroin addiction. METHODS: DNA from 325 methadone stabilized, former severe heroin addicts and 250 control individuals were pooled by ethnicity (Caucasian and African-American) and analyzed using the Affymetrix GeneChip Mapping 100 K Set. Genome-wide association tests were conducted....
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