Article
Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid dependence.
Frontiers in bioscience (Elite edition) - 1 Jan 2018
Blum Kenneth, Chen Amanda L C, Thanos Panayotis K, Febo Marcelo, Demetrovics Zsolt, Dushaj Kristina, Kovoor Abraham, Baron David, Smith David E, Roy Alphonso Kenison, Fried Lyle, Chen Thomas J H, Chapman Edwin, Modestino Edward J, Steinberg Bruce, Badgaiyan Rajendra D
Abstract excerpt
The interaction of neurotransmitters and genes that control the release of dopamine is the Brain Reward Cascade (BRC). Variations within the BRC, whether genetic or epigenetic, may predispose individuals to addictive behaviors and altered pain tolerance. This discussion authored by a group of concerned scientists and clinicians examines the Genetic Addiction Risk Score (GARS), the first test to accurately predict...
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