Article

The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci

2022-05-18

Abstract excerpt

Vascular sites have distinct susceptibility to atherosclerosis and aneurysm, yet the biological underpinning of vascular site-specific disease risk is largely unknown. Vascular tissues have different developmental origins that may influence global chromatin accessibility, and understanding differential chromatin accessibility, gene expression profiles, and gene regulatory networks (GRN) on single cell resolution m...

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Literature Corpus work: 08bf77c3-b3af-5c35-989e-f88f8dc4551c
DOI: 10.1101/2022.05.18.492517

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