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Article

Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in <i>Mycobacterium tuberculosis</i>

2019-12-13

Abstract excerpt

Diversity of the CRISPR locus of Mycobacterium tuberculosis complex has been studied since 1997 for molecular epidemiology purposes. By targeting solely the 43 spacers present in the two first sequenced genomes (H37Rv and BCG), it gave a biased idea of CRISPR diversity and ignored diversity in the neighbouring cas -genes. We set up tailored pipelines to explore the diversity of CRISPR-cas locus in Short Reads....

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Identifiers and source

Literature Corpus work
083726e9-734f-5d12-bce5-759bef9421ee
DOI
10.1101/2019.12.13.875765
Open publication

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Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in <i>Mycobacterium tuberculosis</i>DOI 10.1101/2019.12.13.875765
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