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Article

Structure and variation of CRISPR and CRISPR-flanking regions in deleted-direct repeat region Mycobacterium tuberculosis complex strains.

BMC genomics - 15 Feb 2017

Freidlin Paul Jeffrey, Nissan Israel, Luria Anna, Goldblatt Drora, Schaffer Lana, Kaidar-Shwartz Hasia, Chemtob Daniel, Dveyrin Zeev, Head Steven Robert, Rorman Efrat

Abstract excerpt

BACKGROUND: CRISPR and CRISPR-flanking genomic regions are important for molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) strains, and potentially for adaptive immunity to phage and plasmid DNA, and endogenous roles in the bacterium. Genotyping in the Israel National Mycobacterium Reference Center Tel-Aviv of over 1500 MTBC strains from 2008-2013 showed three strains with validated negative...

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Source

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Identifiers

PMID: 28201993
DOI: 10.1186/s12864-017-3560-6
PMCID: PMC5310062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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