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Article

Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus.

Journal of bacteriology - 1 Feb 2008

Horvath Philippe, Romero Dennis A, Coûté-Monvoisin Anne-Claire, Richards Melissa, Deveau Hélène, Moineau Sylvain, Boyaval Patrick, Fremaux Christophe, Barrangou Rodolphe

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR) are hypervariable loci widely distributed in prokaryotes that provide acquired immunity against foreign genetic elements. Here, we characterize a novel Streptococcus thermophilus locus, CRISPR3, and experimentally demonstrate its ability to integrate novel spacers in response to bacteriophage. Also, we analyze CRISPR diversity and activity across...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18065539
DOI: 10.1128/JB.01415-07
PMCID: PMC2238196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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