Article
Whole-genome single nucleotide variant phylogenetic analysis of Mycobacterium tuberculosis Lineage 1 in endemic regions of Asia and Africa.
Scientific reports - 28 Jan 2022
Netikul Thidarat, Thawornwattana Yuttapong, Mahasirimongkol Surakameth, Yanai Hideki, Maung Htet Myat Win, Chongsuvivatwong Virasakdi, Palittapongarnpim Prasit
Abstract excerpt
Mycobacterium tuberculosis (Mtb) lineage 1 (L1) contributes considerably to the disease morbidity. While whole genome sequencing (WGS) is increasingly used for studying Mtb, our understanding of genetic diversity of L1 remains limited. Using phylogenetic analysis of WGS data from endemic range in Asia and Africa, we provide an improved genotyping scheme for L1. Mapping deletion patterns of the 68 direct variable...
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