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Article

CRISPR Diversity and Microevolution in<i>Clostridium difficile</i>

29 Aug 2016

Abstract excerpt

Virulent strains of Clostridium difficile have become a global health problem associated with morbidity and mortality. Traditional typing methods do not provide ideal resolution to track outbreak strains, ascertain genetic diversity between isolates, or monitor the phylogeny of this species on a global basis. Here, we investigate the occurrence and diversity of clustered regularly interspaced short palindromic...

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PMID: 27576538
DOI: 10.1093/gbe/evw203

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