Back to search

Article

Fatty Acid Synthase-Derived Lipid Stores Support Breast Cancer Metastasis

2024-12-05

Abstract excerpt

<title>Abstract</title> <p>Lipid accumulation is associated with breast cancer metastasis. However, the mechanisms underlying how breast cancer cells increase lipid stores and their functional role in disease progression remain incompletely understood. Herein we quantified changes in lipid metabolism and characterized cytoplasmic lipid droplets in metastatic versus non-metastatic breast cancer cells. <sup>14</sup...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
08112014-9e46-5e37-b1b0-b5dc04196698
DOI
10.21203/rs.3.rs-5510550/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Fatty Acid Synthase-Derived Lipid Stores Support Breast Cancer MetastasisDOI 10.21203/rs.3.rs-5510550/v1
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escapeSemantic proximity
Lipogenesis-driven EGFR palmitoylation enables metastatic immune evasion in triple-negative breast cancerSemantic proximity
Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulationSemantic proximity
New dawn for cancer cell death: Emerging role of lipid metabolismSemantic proximity
Spatial Gene Expression Analysis Reveals Drivers of Extremely Early Lymph Node Metastasis in Breast CancerSemantic proximity
Adipocyte mesenchymal transition contributes to mammary tumor progressionSemantic proximity
ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expressionSemantic proximity
Lipid metabolic reprogramming drives triglyceride storage and variable sensitivity to FASN inhibition in endocrine-resistant breast cancer cellsSemantic proximity
Acetyl-CoA carboxylase 1-dependent lipogenesis drives breast cancer progressionSemantic proximity
Adenosine triphosphate citrate lyase alters cellular myelocytomatosis oncogene signaling and fatty acid oxidation in residual breast cancer tumor tissues after neoadjuvant treatmentSemantic proximity
Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer.Semantic proximity
FADS2-mediated fatty acid desaturation and cholesterol esterification are signatures of metabolic reprogramming during melanoma progressionSemantic proximity
Select a neighboring publication to make it the new centre.