Article

Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation

2024-01-24

Abstract excerpt

Phenotypic diversity of cancer cells within tumors generated through bi-directional interactions with the tumor microenvironment has emerged as a major driver of disease progression and therapy resistance. Nutrient availability plays a critical role in determining phenotype, but whether specific nutrients elicit different responses on distinct phenotypes is poorly understood. Here we show, using melanoma as a mode...

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Literature Corpus work: fcb7c79c-6ea1-54c5-b943-4637a51fcbde
DOI: 10.1101/2024.01.21.576568

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