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A serum protein signature of APOE genotypes in centenarians

5 Aug 2019

Abstract excerpt

Abstract The discovery of treatments to prevent or delay dementia and Alzheimer's disease is a priority. The gene APOE is associated with cognitive change and late‐onset Alzheimer's disease, and epidemiological studies have provided strong evidence that the e2 allele of APOE has a neuroprotective effect, it is associated with increased longevity and an extended healthy lifespan in centenarians. In this study, we...

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PMID: 31385390
DOI: 10.1111/acel.13023

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