Article

Conversion to Parkinsonism and Dementia in REM-Sleep Behavior Disorder Using the Chronobiotic Melatonin

2020-11-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Isolated REM sleep behavior disorder (iRBD), a reliable prodromal stage marker of α-synucleinopathies like Parkinson’s disease or Lewy body dementia, offers an early window for disease-modifying intervention. Current treatments of iRBD, including the two level B therapies with clonazepam and melatonin, are considered symptomatic. However, numbers of reported patients treated w...

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Literature Corpus work: ac35e84a-74dd-55a1-b764-26dec84f85e0
DOI: 10.1101/2020.11.05.20224592

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