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Article

Stonewalling Drosophila stem cell differentiation by epigenetic controls.

Development (Cambridge, England) - 1 Apr 2007

Maines Jean Z, Park Joseph K, Williams Meredith, McKearin Dennis M

Abstract excerpt

During Drosophila oogenesis, germline stem cell (GSC) identity is maintained largely by preventing the expression of factors that promote differentiation. This is accomplished via the activity of several genes acting either in the GSC or in its niche. The translational repressors Nanos and Pumilio act in GSCs to prevent differentiation, probably by inhibiting the translation of early differentiation factors,...

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Source

Identifiers

PMID: 17344229
DOI: 10.1242/dev.02810

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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