Article

Characterization of factors that underlie transcriptional silencing in <i>C. elegans</i> oocytes

2022-08-28

Abstract excerpt

<h4>Abstract/Summary</h4> While it has been appreciated for decades that prophase-arrested oocytes are transcriptionally silenced on a global level, the molecular pathways that promote silencing have remained elusive. Previous work in C. elegans has shown that both topoisomerase II (TOP-2) and condensin II collaborate with the H3K9me heterochromatin pathway to silence gene expression in the germline during L1 st...

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Literature Corpus work: e95dad00-39d5-5b13-a110-9cd8e5eb1806
DOI: 10.1101/2022.08.28.505591

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