Article

Spatial coupling between DNA replication and mismatch repair in <i>Caulobacter crescentus</i>

2020-07-13

Abstract excerpt

<h4>ABSTRACT</h4> The DNA mismatch repair (MMR) process detects and corrects replication errors in organisms ranging from bacteria to humans. In most bacteria, it is initiated by MutS detecting mismatches and MutL nicking the mismatch-containing DNA strand. Here, we show that MMR reduces the appearance of rifampicin resistances more than a 100-fold in the Caulobacter crescentus Alphaproteobacterium . Using fluor...

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Literature Corpus work: 078269c6-a862-5666-a587-9cd729deac12
DOI: 10.1101/2020.07.13.200147

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