Article

C1q limits cystoid edema by maintaining basal beta-catenin-dependent signaling and blood-retina barrier function

2025-07-26

Abstract excerpt

Macular edema (ME) causes significant vision impairment and occurs in several prevalent retinal diseases including diabetic retinopathy (DR), choroidal neovascularization (CNV), retinal vein occlusion, and uveitis. Retinal edema typically results from dysfunction of the blood-retina barrier (BRB), which is associated with increased retinal expression of complement components. It is unclear whether the classical co...

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Identifiers and source

Literature Corpus work: 0733d403-8ef9-522d-9b34-3cb75043674c
DOI: 10.1101/2025.07.22.666172

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