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Article

C1q as a target molecule to treat human disease: What do mouse studies teach us?

3 Aug 2022

Abstract excerpt

The complement system is a field of growing interest for pharmacological intervention. Complement protein C1q, the pattern recognition molecule at the start of the classical pathway of the complement cascade, is a versatile molecule with additional non-canonical actions affecting numerous cellular processes. Based on observations made in patients with hereditary C1q deficiency, C1q is protective against systemic...

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PMID: 35990646
DOI: 10.3389/fimmu.2022.958273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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