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Therapeutic targeting of the complement system in ocular disease

30 Aug 2023

Abstract excerpt

The complement system is involved in the pathogenesis of several ocular diseases, providing a rationale for the investigation of complement-targeting therapeutics for these conditions. Dry age-related macular degeneration, as characterised by geographic atrophy (GA), is currently the most active area of research for complement-targeting therapeutics, with a complement C3 inhibitor approved in the United States...

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PMID: 37657753
DOI: 10.1016/j.drudis.2023.103757

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