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Article

The alternative complement pathway regulates pathological angiogenesis in the retina

25 Mar 2014

Abstract excerpt

A defining feature in proliferative retinopathies is the formation of pathological neovessels. In these diseases, the balance between neovessel formation and regression determines blindness, making the modulation of neovessel growth highly desirable. The role of the immune system in these retinopathies is of increasing interest, but it is not completely understood. We investigated the role of the alternative...

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PMID: 24668752
DOI: 10.1096/fj.14-251041

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