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Article

Human ESCRT-III Polymers Assemble on Positively Curved Membranes and Induce Helical Membrane Tube Formation

2019-11-20

Abstract excerpt

Endosomal sorting complexes required for transport-III (ESCRT-III) are thought to assemble in vivo inside membrane structures with a negative Gaussian curvature. How membrane shape influences ESCRT-III polymerization and conversely how ESCRT-III polymers shape membranes is still unclear. Here, we used human core ESCRT-III proteins, CHMP4B, CHMP2A, CHMP2B and CHMP3 to address this issue in vitro by combining memb...

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Identifiers and source

Literature Corpus work
0713e808-83f7-5c66-9727-eb04a05aec6a
DOI
10.1101/847319
Open publication

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Human ESCRT-III Polymers Assemble on Positively Curved Membranes and Induce Helical Membrane Tube FormationDOI 10.1101/847319
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