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Article

The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices.

Cell - 12 Oct 2012

Henne William Mike, Buchkovich Nicholas J, Zhao Yingying, Emr Scott D

Abstract excerpt

The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that mediate topologically similar membrane-sculpting processes, including cytokinesis, retroviral egress, and multivesicular body (MVB) biogenesis. Although ESCRT-III drives membrane remodeling that creates MVBs, its structure and the mechanism of vesicle formation are unclear. Using electron microscopy, we...

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PMID: 23063125
DOI: 10.1016/j.cell.2012.08.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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