Article
Plasma membrane deformation by circular arrays of ESCRT-III protein filaments.
The Journal of cell biology - 28 Jan 2008
Hanson Phyllis I, Roth Robyn, Lin Yuan, Heuser John E
Abstract excerpt
Endosomal sorting complex required for transport III (ESCRT-III) proteins function in multivesicular body biogenesis and viral budding. They are recruited from the cytoplasm to the membrane, where they assemble into large complexes. We used "deep-etch" electron microscopy to examine polymers formed by the ESCRT-III proteins hSnf7-1 (CHMP4A) and hSnf7-2 (CHMP4B). When overexpressed, these proteins target to...
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