Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shiga Toxins: An Update on Host Factors and Biomedical Applications

18 Mar 2021

Abstract excerpt

(EHEC). These toxins recognize a glycosphingolipid globotriaosylceramide (Gb3/CD77) as their receptor and inhibit protein synthesis in cells by cleaving 28S ribosomal RNA. They are the major cause of life-threatening complications such as hemolytic uremic syndrome (HUS), associated with severe cases of EHEC infection, which is the leading cause of acute kidney injury in children. The threat of Stxs is exacerbated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli research studies
Share to Transgenic Plants and Applications
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33803852
DOI: 10.3390/toxins13030222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shiga Toxins: An Update on Host Factors and Biomedical ApplicationsPMID 33803852Read ↗

Shiga toxin-associated hemolytic uremic syndrome: advances in pathogenesis and therapeutics.Semantic proximity Read ↗

CRISPR screen reveals that EHEC’s T3SS and Shiga toxin rely on shared host factors for infectionSemantic proximity Read ↗

Molecular Biology of Escherichia coli Shiga Toxins’ Effects on Mammalian CellsSemantic proximity Read ↗

CRISPR Screen Reveals that EHEC's T3SS and Shiga Toxin Rely on Shared Host Factors for Infection.Semantic proximity Read ↗

Shiga toxins and stx phages: highly diverse entitiesSemantic proximity Read ↗

Treatment of STEC infection via CRISPR-Cas targeted cleavage of the Shiga toxin gene in animal modelsSemantic proximity Read ↗

A Comprehensive Review on Shiga Toxin Subtypes and Their Niche-Related Distribution Characteristics in Shiga-Toxin-Producing E. coli and Other Bacterial HostsSemantic proximity Read ↗

Bacteriophages Carrying Shiga Toxin Genes: Genomic Variations, Detection and Potential Treatment of Pathogenic BacteriaSemantic proximity Read ↗

Pathogenesis and Diagnosis of Shiga Toxin-Producing <i>Escherichia coli</i> InfectionsSemantic proximity Read ↗

Shiga toxin remodels the intestinal epithelial transcriptional response to Enterohemorrhagic Escherichia coliSemantic proximity Read ↗

Genetics, Toxicity, and Distribution of Enterohemorrhagic Escherichia coli HemolysinSemantic proximity Read ↗

A new paradigm of bacteria-gut interplay brought through the study of <bold>Shigella</bold>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.