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Article

Immune-based subgroups uncover diverse tumor immunogenicity and implications for prognosis and precision therapy in acute myeloid leukemia.

Frontiers in immunology - 1 Jan 2024

Chen Tingting, Zhang Yue, Zhang Danyang, Zhou Hebing

Abstract excerpt

Background: Although a considerable proportion of acute myeloid leukemia (AML) patients achieve remission through chemotherapy, relapse remains a recurring and significant event leading to treatment failure. This study aims to investigate the immune landscape in AML and its potential implications for prognosis and chemo-/immune-therapy. Methods: Integrated analyses based on multiple sequencing datasets of AML...

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Identifiers

PMID: 39582863
DOI: 10.3389/fimmu.2024.1451486
PMCID: PMC11581856

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