Article

Immunological landscape of human lymphoid explants during measles virus infection

2022-09-13

Abstract excerpt

In humans, lymph nodes are the primary site of measles virus (MeV) replication. To understand the immunological events that occur at this site, we infected human lymphoid tissue explants using a pathogenic strain of MeV that expresses GFP. We found that MeV infected between 5-15% of cells across donors. Using single cell RNA-Seq (scRNA-Seq) and flow cytometry, we found that while most of the 29 cell populations id...

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Literature Corpus work: 0683cd84-8374-57cc-8597-c943bf5249e4
DOI: 10.1101/2022.09.12.507535

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