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dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity

26 Aug 2011

Abstract excerpt

The innate immune system detects viruses through molecular sensors that trigger the production of type I interferons (IFN-I) and inflammatory cytokines. As viruses vary tremendously in size, structure, genomic composition, and tissue tropism, multiple sensors are required to detect their presence in various cell types and tissues. In this review, we summarize current knowledge of the diversity, specificity, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21884168
DOI: 10.1111/j.1600-065x.2011.01049.x

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