Article
Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Kaletsky Rachel, Murphy Coleen T
Abstract excerpt
Multicellular organisms are composed of distinct cells and tissues that coordinate highly orchestrated responses to environmental challenges, including those that arise with age. Since C. elegans is a premier model system used to study the molecular and cellular regulators of adult and aging phenotypes, cell type- and tissue-specific approaches are needed to characterize the genome-wide expression changes...
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