Article

Human <i>CEBPA</i> -N AML exhibits enhanced engraftment and a C/EBP <i>α</i> -p30-driven leukemic stem cell program

2026-08-04

Abstract excerpt

Leukemic stem cells (LSCs) play a central role in disease progression, therapeutic resistance, and relapse in acute myeloid leukemia (AML). However, the identification and characterization of LSCs remain challenging because of their low abundance and their close phenotypic resemblance to normal hematopoietic stem and progenitor cells. Although patient-derived xenograft (PDX) models have provided important insights...

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Literature Corpus work: 04e7f43c-b72f-5215-bd65-f64eeb7eba8a
DOI: 10.64898/2026.08.03.742558

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