Article

Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia

2023-09-04

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in hematopoietic stem/progenitor cells (HSPCs) can remain dormant within the bone marrow (BM) for decades before leukemia onset. Understanding the mechanisms by which these mutant clones eventually slead to full blown leukemia is of critical importance to develop strategies to eliminate these clones before they achieve their full leukemogenic potential. Recent data suggest that leukemi...

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Literature Corpus work: 65cefff1-0e06-5fe2-8e06-d5db83859db9
DOI: 10.1101/2023.09.01.553259

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