Article

Spontaneous Pregravid Obesity Reshapes Fetal Immune Ontogeny in a Nonhuman Primate Model

2026-03-31

Abstract excerpt

Pregravid obesity is associated with long⍰term immune alterations in the offspring; however, the mechanisms remain poorly defined. To address this gap, we investigated the impact of spontaneous pregravid obesity, independent of obesogenic diet, on fetal immune ontogeny in a rhesus macaque model. Using spectral flow cytometry, multiplex cytokine profiling, functional stimulation assays, and single⍰cell RNA sequenci...

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Literature Corpus work: 04797c65-21b2-5dc1-adf4-eb31f3ff6ad1
DOI: 10.64898/2026.03.27.714880

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