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A dynamic peripheral immune landscape during human pregnancy

30 Jun 2022

Abstract excerpt

Extensive immune adaptations occur during pregnancy to ensure successful delivery. However, these changes can increase the risk of disease in the mother. Here, we conducted single-cell RNA sequencing on peripheral blood mononuclear cells from pregnant women at different stages of pregnancy to elucidate the dynamic transcriptional changes in the maternal immune system. Gradual reduced cytotoxicity phenotype in...

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PMID: 40166108
DOI: 10.1016/j.fmre.2022.06.011

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