Article

Triacylglycerol synthesis enhances macrophage inflammatory function

2020-02-05

Abstract excerpt

Macrophages are integral to most tissues. Foam cells, macrophages with lipid droplets (LDs) which are stores of triacylglycerols (TGs) and cholesterol esters (CEs), are found in various disease states 1 . LDs can act as energy stores since TG lipolysis releases fatty acids (FAs) for mitochondrial oxidation (FAO), a process that relies on long-chain FA conversion into acylcarnitines by the enzyme Cpt1a 2 . Howeve...

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Literature Corpus work: 04730197-86a7-5b87-afca-6f89c698928a
DOI: 10.1101/2020.02.03.932079

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