Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Palmitate differentially regulates the polarization of differentiating and differentiated macrophages.

Immunology - 1 Jan 2016

Xiu Fangming, Diao Li, Qi Peter, Catapano Michael, Jeschke Marc G

Abstract excerpt

The tissue accumulation of M1 macrophages in patients with metabolic diseases such as obesity and type 2 diabetes mellitus has been well-documented. Interestingly, it is an accumulation of M2 macrophages that is observed in the adipose, liver and lung tissues, as well as in the circulation, of patients who have had major traumas such as a burn injury or sepsis; however, the trigger for the M2 polarization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents
Share to Endoplasmic Reticulum Stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DR1 Antigen

Share to Inflammation Mediators

Share to Macrophage Activation

Share to Palmitic Acid

Share to Phagocytosis

Share to PPAR gamma

Source

Open in PubMed Open full text

Identifiers

PMID: 26453839
DOI: 10.1111/imm.12543
PMCID: PMC4693883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Palmitate differentially regulates the polarization of differentiating and differentiated macrophages.PMID 26453839Read ↗

Treatment with sitagliptin exacerbates the M2 phenotype in macrophages in vitro.Semantic proximity Read ↗

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?Semantic proximity Read ↗

Contribution of Macrophage Polarization to Metabolic Diseases.Semantic proximity Read ↗

Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β-oxidation deficiency.Semantic proximity Read ↗

The roles of macrophage polarization in the host immune response to sepsis.Semantic proximity Read ↗

Macrophages, meta-inflammation, and immuno-metabolism.Semantic proximity Read ↗

Diesel exhaust particles induce polarization state-dependent functional and transcriptional changes in human monocyte-derived macrophages.Semantic proximity Read ↗

The role of immunometabolism in macrophage polarization and its impact on acute lung injury/acute respiratory distress syndromeSemantic proximity Read ↗

Regulatory mechanisms of macrophage polarization in adipose tissueSemantic proximity Read ↗

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes.Semantic proximity Read ↗

Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolismSemantic proximity Read ↗

The Role of Metabolic Remodeling in Macrophage Polarization and Its Effect on Skeletal Muscle Regeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.