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Article

CPT1A-IL-10-mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury.

Clinical and translational medicine - 1 Aug 2024

Wang Muyun, Wu Di, Liao Ximing, Hu Haiyang, Gao Jing, Meng Linlin, Wang Feilong, Xu Wujian, Gao Shaoyong, Hua Jing, Wang Yuanyuan, Li Qiang, Wang Kun, Gao Wei

Abstract excerpt

BACKGROUND: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common acute respiratory failure due to diffuse pulmonary inflammation and oedema. Elaborate regulation of macrophage activation is essential for managing this inflammatory process and maintaining tissue homeostasis. In the past decades, metabolic reprogramming of macrophages has emerged as a predominant role in modulating their...

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Identifiers

PMID: 39090662
DOI: 10.1002/ctm2.1785
PMCID: PMC11294017

Genes

CPT1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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